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Journal of the Korea Institute of Military Science and Technology 2004;7(4):87-90.
Expression Patterns of P21-Activated Kinase 2 by Sterne Spores on Human Macrophages
Gwi-Moon Seo, Kwang-Hwa Jung, Hyun Jung Kwak, Seong-Joo Kim, Ji-Chon Kim, Young-Gyu Chai
Hanyang University
사람 대식세포에 스턴아포에 처리에 의한 P21-activated kinase 2 단백질의 발현양상
서귀문, 정경화, 곽현정, 김성주, 김지천, 채영규
한양대학교
Abstract
In order to elucidate the mechanism of infection on human macrophages, we peformed the 2-dimensional electrophoresis and the western blot analysis using the infected human macrophages with the spores of live and inactivated Sterne. We confirmed P21-activated kinase 2 protein which related to cell death(apoptosis) human macrophages at the early stage events. The inhibition of the P21-activated protein kinase 2 protein will be reduced apoptosis on infected human macrophages with Sterne spores.
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